Program Directors

Katherine Nathanson, MD

Katherine Nathanson, MD

Pearl Basser Professor for BRCA-Related Research at the Abramson Cancer Center of the University of Pennsylvania

Dr. Katherine Nathanson is a Professor of Medicine in the Division of Translational Medicine and Human Genetics. She also serves as the Associate Director of Population Science, Co-Leader of the Cancer Control Program and Chief Oncogenomics Physician in the Abramson Cancer Center. She was dually trained in Internal Medicine and Clinical Genetics, and so has been practicing Genomic Medicine for her entire career. She has a well-funded NIH-funded research program in the inherited and somatic genetics/genomics of cancer. She has been elected to the American Society of Clinical Investigation and American Association of Physicians. Dr. Nathanson has trained over 25 undergraduates, graduate students, medical residents, and post-doctoral fellows. She co-led the Cancer Biology (Cellular and Molecular Biology) introductory course for three years, and has served on multiple preliminary and thesis committees. She directed the Medical Genetics rotation in Adult Genetics, and the Internal Medicine resident rotation in Medical Genetics for over 10 years. She serves on the Residency Committee for Medical Genetics, on the admissions committee for the MD-PhD program and as co-PI for the Medical Genetics Research Training Grant.

Marylyn D. Ritchie, PhD

Director of the Institute for Biomedical Informatics

Marylyn D. Ritchie, PhD is a Professor in the Department of Genetics, Director of the Center for Translational Bioinformatics, Associate Director for Bioinformatics in the Institute for Biomedical Informatics at the University of Pennsylvania School of Medicine. Dr. Ritchie is also Associate Director for the Penn Center for Precision Medicine. Dr. Ritchie is a translational bioinformatics scientist, biomedical informatician, and computational human geneticist with a focus on developing novel approaches for understanding the relationship between our genome and human phenotypes. She has expertise in developing novel bioinformatics tools for complex analysis of big data in genetics, genomics, and clinical databases, in particular in the area of Pharmacogenomics. Some of her methods include Multifactor Dimensionality Reduction (MDR), the Analysis Tool for Heritable and Environmental Network Associations (ATHENA), and the Biosoftware suite for annotating/ filtering variants and genomic regions as well as building models of biological relevance for gene-gene interactions and rare-variant burden/dispersion tests. Dr. Ritchie has over 15 years of experience in the analysis of complex data and has authored over 300 publications.  Dr. Ritchie has received several awards and honors including selection as a Genome Technology Rising Young Investigator in 2006, an Alfred P. Sloan Research Fellow in 2010, a KAVLI Frontiers of Science fellow by the National Academy of Science from 2011-2014, and she was named one of the most highly cited researchers in her field by Thomas Reuters in 2014. Dr. Ritchie has extensive experience in all aspects of genetic epidemiology and translational bioinformatics as it relates to human genomics. She also has extensive expertise in dealing with big data and complex analysis including GWAS, next-generation sequencing, data integration of meta-dimensional omics data, Phenome-wide Association Studies (PheWAS), and development of data visualization approaches.

Current Trainees

Leslie Andriani, MD

Leslie Andriani, MD

Clinical Fellow, University of Pennsylvania

Laura Colbran , PhD

Laura Colbran, PhD

Postdoctoral Fellow, University of Pennsylvania

Danielle Gutman, PhD

Danielle Gutman, PhD

Postdoctoral Fellow, University of Pennsylvania

Kelsey Lau-Min, MD

Kelsey Lau-Min, MD

Clinical Fellow, University of Pennsylvania

Angela Liou, MD

Clinical Fellow, Children's Hospital of Philadelphia

Katherine Tsukahara, MD

Katherine Tsukahara, PhD

Clinical Fellow, Children's Hospital of Philadelphia

Trainers